Laura Luebbert joins the podcast to discuss her pivot from wet lab neuroscience to computational biology and the development of her widely used bioinformatics tool, "gget." We explore how she identifies viral sequences in genomic data, the challenges of maintaining open-source software, and her experience navigating scientific integrity issues as an early-career researcher.
Read More98. Laura Wesseldijk: Behavioural genetics, music, and the importance of twins
Is musical talent all in your genes? Laura Wesseldijk joins the podcast to discuss her research on the genetics of musicality, including the surprising finding that Beethoven had a low genetic predisposition for beat synchronization. We explore how twin studies and genome-wide association studies (GWAS) are unraveling the complex interplay between nature and nurture in musical ability, and why starting piano lessons early might not be the magic bullet we think it is.
Read More97. Arne Ekstrom: Spatial navigation, memory, and invasive recordings in humans
Is the hippocampus just a GPS, or is it the brain's ultimate multitasker? Arne Ekstrom joins the podcast to discuss his groundbreaking work recording single neurons in the human brain. We explore the discovery of "place cells" in humans, the surprising role of the hippocampus in memory beyond navigation, and why he believes the brain is more like a versatile network than a collection of specialized modules.
Read More96. Benjamin Ehrlich: Santiago Ramon y Cajal, the neuron doctrine, and combining art & science
Is the brain a continuous web or a network of cells? Benjamin Ehrlich joins the podcast to discuss the life and work of Santiago Ramón y Cajal, the "father of neuroscience." We explore how a rebellious young artist became the most important figure in brain science, his rivalry with Camillo Golgi, and why his beautiful drawings of neurons are still used in textbooks today.
Read More95. Emily Finn: Neural fingerprinting, 'naturalistic' stimuli, and taking time before starting a PhD
Is your brain's connectivity pattern as unique as your fingerprint? Emily Finn joins the podcast to discuss her pioneering work on "neural fingerprinting," where she showed that an individual's brain connectivity can be used to identify them with surprising accuracy. We explore her journey from studying linguistics and working in the coffee industry in Peru to becoming a neuroscientist, the potential of movie-watching paradigms in fMRI , and why the "reliability paradox" is a challenge for cognitive tasks.
Read More94. David Van Essen: The Human Connectome Project, hierarchical processing, and the joys of collaboration
Is the brain a hierarchy or a chaotic mess? David Van Essen joins the podcast to discuss his groundbreaking work mapping the visual cortex and the Human Connectome Project. We explore his journey from building rockets as a child to collaborating with Nobel laureates, the evolution of cortical cartography, and why 180 is the magic number for brain areas.
Read More93. Nachum Ulanovsky: Bats, spatial navigation, and natural neuroscience
Is the hippocampus really a GPS? Nachum Ulanovsky joins the podcast to discuss his groundbreaking work with Egyptian fruit bats. We explore how bats encode 3D space, why he built a 700-meter tunnel for them to fly through, and the discovery of "social place cells" that track other individuals.
Read More92. Tom Hardwicke: Meta-research, reproducibility, and post-publication critique
Tom Hardwicke details his transition from a disillusioned PhD student to a meta-researcher tackling the structural flaws of scientific publishing. We discuss why journals restrict post-publication critique, the nuances of data transparency, and his new role enhancing rigor at Psychological Science.
Read More91. Jessica Polka: Preprints, publishing peer reviews, and the joys of pipetting
Is the scientific paper outdated? Jessica Polka joins the podcast to discuss the future of publishing and why preprints are shaking up the status quo. We explore how "publish or perish" distorts science, the benefits of open peer review, and her transition from the lab bench to full-time advocacy for research transparency.
Read More90. Brian Boyd: The life & works of Vladimir Nabokov, Lolita, and writing biographies
Brian Boyd joins the podcast to discuss the life and work of Vladimir Nabokov, author of Lolita. We explore Nabokov's multilingual upbringing, his escape from the Russian Revolution, why Lolita is studied by sexual abuse therapists, and the hidden clues buried in his most complex novel, Pale Fire.
Read More89. Camillo Padoa-Schioppa: Value in the brain, orbitofrontal cortex, and causality in neuroscience
Is economic value real, or just a convenient illusion? Camillo Padoa-Schioppa joins the podcast to discuss his pioneering research on the neural basis of decision-making. We explore the history of economic thought from Homer to Samuelson, whether the brain encodes value, and causality in neuroscience.
Read More88. Juliana Schroeder: Talking to strangers, undersociality, and replicable field studies
Is talking to strangers really that scary? Juliana Schroeder joins the podcast to discuss her research on the unexpected benefits of connecting with people during your daily commute. We explore why we mistakenly assume strangers don't want to talk, the surprising methods people use to break the ice, and the challenges of conducting psychological research outside the lab.
Read More87. Rick Betzel: Network neuroscience, generative modeling, and collaborations
Rick Betzel joins the podcast to discuss the future of network neuroscience. We explore how generative models can simulate brain growth , the promise of "edge-centric" connectomics for tracking moment-to-moment brain activity, and his journey from baseball biomechanics to brain networks.
Read More86. Elisabeth Bik: Reporting scientific misconduct, the arms race between fraud & fraud detection, and the microbiome of dolphins
Elisabeth Bik, one of the world's most famous scientific sleuth, joins the podcast to discuss hunting down image manipulation and data fraud. We explore how she spots fake Western blots, deals with online harassment and legal threats from powerful academics, and why the "Tadpole Paper Mill" taught fraudsters to cheat better.
Read More85. Peter Bandettini: The history, present, and future of fMRI
Is the future of brain imaging faster, deeper, or more precise? Peter Bandettini joins the podcast to reflect on the serendipitous birth of fMRI and his pivotal role in its early days. We explore how scanning a single person for 10 hours reveals hidden brain activity, the surprising promise of layer fMRI, and why the most important discoveries often start as noise.
Read More84. Brian Nosek: Improving science, the past & future of the Center for Open Science, and failure in science
Is science broken? Brian Nosek has spent the last decade trying to fix it. He joins the podcast to discuss how he turned a graduate student frustration into the Center for Open Science, a multi-million dollar non-profit that has revolutionized research transparency. We explore the "reproducibility crisis" in psychology, the importance of "getting it right over being right," and why he thinks we should embrace stupidity in scientific research.
Read More83. Rachel Bedder: Rumination, teaching without grades, and managing yourself as a PhD student
Is rumination a problem of sampling too much? Rachel Bedder joins the podcast to discuss how computational models can explain repetitive negative thinking. We explore her work teaching math in a New Jersey prison, the benefits of "ungrading" in university courses, and how a background in art influences her approach to science.
Read More82. Geoff Cumming: p-values, estimation, and meta-analytic thinking
Is the p-value dead? Geoff Cumming joins the podcast to argue for a "New Statistics" based on estimation and confidence intervals. We discuss the dance of the p-values, why we should ditch post-hoc power calculations for "precision for planning," and how meta-analytic thinking can revolutionize scientific research.
Read More81. Brooke Macnamara: Growth mindset, deliberate practice, and the benefits of diverse experiences
Brooke Macnamara joins the podcast to discuss her meta-analyses challenging the popular theories of "Deliberate Practice" and "Growth Mindset." We explore why practicing more doesn't always make you the best, why mindset interventions often fail to boost grades, and what actually separates elite performers from the rest.
Read More80. Simine Vazire: Scientific editing, the purpose of journals, and the future of psychological science
Is the peer review system doing its job? Simine Vazire joins the podcast to discuss her plans as the incoming editor-in-chief of Psychological Science. We talk about the hidden curriculum of academic publishing, why she resigned from a prestigious National Academy of Sciences committee, and her involvement in the "Data Colada" legal defense fundraiser.
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